Cadina

Cadina is the femslash ship between Regina George and Cady Heron from the Mean Girls fandom.

Canon
Regina and Cady met each other at school. Cady is the new girl from Africa (the country where she comes from is never specified), who is having a hard time adjusting to the US' school system. And Regina is the "queen bee" of school, the most popular, as well as the leader of the "Mean Girls". Cady gets close with some kids in her class, Damian and Janis, and they introduce her to Regina. The first time Cady learns from Regina, she hears she's the most evil person, and Cady stares at her from afar, smiling slightly.

Their very first interaction happens at the school cafeteria, when Regina blocks the sexual advancements of a boy who was hitting on Cady. She sarcastically asks Cady if she wants to have sex with the boy, to which Cady uncomfortably replies "no, thank you." This causes Regina to shoo off the boy who was bothering Cady. She then asks Cady to sit with them, which is extremely unusual for her to do, and immediately remarks that Cady is "really pretty." Regina then bends the rules of her own group just to let Cady in.

Regina also immediately allows Cady to join in their daily rituals, instead of making her earn their friendship. She even invites Cady into her house, letting her borrow her clothes. This is very telling since Regina is a supposed "authoritarian" leader with very strict roles. But she shows an immediate interest in Cady that goes beyond what's purely "strategic" or utilitarian. Regina immediately becomes protective of Cady, even, when she tries to protect her from social ridicule as soon as she says she wishes to join the math athletes.

After Regina feels "betrayed" by Cady when she finds out that she was plotting against her, Regina is visibly upset. when she argues with Cady before being crushed by a bus. However, she's able to move on from this, and get better. And when Cady goes to visit her while she recovers, she takes some flowers with her to give them to Regina.

"Mean Girls" deleted scenes
During the prom dance, Cady goes to the bathroom and there, she meets Regina. Seeing her with her adorned spinal halo, Cady immediately tells Regina that she looks really beautiful. She then apologizes to Regina for everything that happened between them, and Regina accepts her apology. Before leaving, Regina gives her a little smile and the two of them go on their separate ways back to the dance.

Fanon
became a really popular ship in the Mean Girls fandom as of recently. Fans started to realize how some of Regina's actions towards Cady can be viewed through a queer-coded lense, and they started seeing the potential in this ship. For example, in the "Mean Girls" deleted scenes, Regina tells Cady that Aaron can't stop talking about Cady, saying Cady is really "unusual." Then Regina goes on a rant about this German doll house she never played with, that her mom wanted to give to Regina's cousin, so she broke it. Because Regina explains that she didn't want anyone else to have that "unusual" thing. Fans started seeing that this whole exchange between them is really vague and that Regina never specifies who she is referring to when talking about the doll house. Which could imply she had a possessive crush on Cady, that made her feel jealous of Aaron. So this fueled the ship even more. Fans also see the potential this ship has when it comes to the "enemies to lovers" trope.

Fandom
FAN FICTION

Trivia

 * As soon as Regina got closer to Cady, she replaced the picture she had with Aaron in her room, to one with Cady.