Amream

Amrean is the femslash ship between Amy Rose and Cream the Rabbit from the Sonic the Hedgehog fandom.

Canon
Amy and Cream have a relationship similar to that of Sonic and Tails, as they have a sister-like bond and Cream is Amy's sidekick. They are members of Team Rose alongside Big the Cat.

Besides the games, Amy and Cream are also best friends in the Archie Comics (from issues released in 2010 until the comics ended) and Sonic X.

Fanon
The pairing has some popularity, although most fans prefer Amy and Cream as friends.

Fandom
DeviantArt
 * amream tag on DeviantArt
 * AmyxCream on Sonic-Yuri-Girls fanclub on DeviantArt

Trivia

 * In Sonic Advance 3, the pairing of Amy and Cream is known as Team Jubilee, making it one of the four pairs (and the only one not involving Sonic) to have a special name.