Amream

Amrean is the femslash ship between Amy Rose and Cream the Rabbit from the Sonic the Hedgehog fandom.

Canon
Amy and Cream have a relationship similar to that of Sonic and Tails, as they have a sister-like bond and Cream is Amy's sidekick. They are members of Team Rose alongside Big the Cat. They have appeared together in multiple games, mostly ones released in the early to mid-2000s.

Their first common appearance was in Sonic Advance 2. They, however, did not have major interactions in that game. In Sonic Heroes, the two teamed up with Big the Cat to find their missing friends (Sonic for Amy, Chocola for Cream and Cheese, Froggy for Big). In Shadow the Hedgehog, Cream and Cheese went missing in Cryptic Castle, and Amy asked Shadow to help her find the two.

Besides the games, Amy and Cream are also best friends in the Archie Comics (from issues released in 2010 until the comics ended) and Sonic X.

Fanon
The pairing has some (but not massive) popularity, although most fans prefer Amy and Cream as friends.

Fandom
DEVIANTART

Trivia

 * In Sonic Advance 3, the pairing of Amy and Cream is known as Team Jubilee, making it one of the four pairs (and the only one not involving Sonic) to have a special name.