When Izuru first meets Nagito he attempted to kill him with a gun after the latter prepared to do the same to Junko. However, because of Nagito's luck, the bullet pierces his student handbook instead. Nagito appears almost immediately attracted to Izuru and Kazutaka Kodaka has described the scene as similar to a beautiful, elegant dance.
Both Izuru and Nagito joined Ultimate Despair in order to get a better look at the battle between hope and despair. Both of them also helped out with Junko and Monaca's plots, respectively, for the very same reason, with Nagito heavily assisting Monaca with her plans by guiding Komaru Naegi to become a symbol of hope, and Izuru being the mastermind of the Killing School Trip.
Izuru is the only person Nagito can physically love (without feeling guilt) Because Izuru cannot be affected by his luck, providing a balance between the two as Izuru simultaneously posses the title of the Super High School Level Good Luck.
When the two meet again (both as members of Ultimate Despair) they do not recognize each other, and while Nagito is very excited about Izuru's company, he merely thinks of him as a completely boring person. This was due to the fact that Izuru asked Junko to erase all memories of him, as he would later erase his own memories about Class 77-B.
In the end, after Hajime Hinata and Izuru's identities have mixed, at first Nagito assumes whom he was talking to was Izuru, but quickly corrects himself calling him Hajime Hinata once more.
The ship already began to sail during Danganronpa 2 era, with the reveal that Izuru Kamukura is an alter ego of Hajime Hinata who already was involved in a ship with Nagito. The fact that Izuru Kamukura has the talents of every Hope's Peak Academy's student ever and as a result is called the "Ultimate Hope" also helped, considering Nagito's obsession with hope.
The scene from Despair Arc's episode 8 in which Izuru steals Nagito's gun and shoots him while Nagito is clearly under impression, all of which shown with more romantic colors, made the ship even more popular than ever, especially since it confimed Nagito's interest in him.
- Izuru's relationship with Nagito on Danganronpa Wiki
- Nagito's relationship with Izuru on Danganronpa Wiki
- Considering Izuru possesess the talents of every Hope's Peak Academy's student ever and also as shown in a scene from episode 8 of Despair Arc, they both possess the Ultimate Luck. However, Izuru's luck appears to outmatch Nagito's, as shown when Nagito's gun jams when he attempts to shoot Kamukura.
- The song "Zettai Kibō Birthday" sung by Nagito is dedicated to Hajime's birthday, but it is implied that Nagito was dedicating it to Izuru because of the passage where he says "the birthday of absolute hope" because Izuru is the Ultimate Hope.
- Kodaka wrote on twitter short fanfic of them.
- The official DR3 anthology manga shows scene in what appears to be reference to Revolutionary Girl Utena,a very known and deeply influential queer anime from the 90s.
- Kamukomahina refers to the ship between the two and Hajime Hinata
- Kamukomanami refers to the ship between the two and Chiaki Nanami
- Matsukamukoma refers to the ship between the two and Yasuke Matsuda